Puffy Zebrafish

Proof, once again, that the kidney is important:

Here's a picture I took of a control (normal) zebrafish at about 2.5 days of life. Note its rather svelte appearance.


When you take away its kidney function (which I can do by knocking down one of its genes) it gets edema--massive fluid accumulation. It doesn't take a zebrafish nephrologist to realize that this fish is totally f'ed up (that's the scientific term...)

Seen from above it looks kind of like a manta ray!