Pacman Fish Movies

I was screwing around using the high-speed camera in our lab yesterday and took this fun movies of a Pac-Man-like heart valve from one of our zebrafish embryos.  Yummy.

Then, I treated the exact same embryo with a drug called 2,3-butanedione monoxime (BDM) which inhibits actin, a critical protein of the cell's internal skeleton which is necessary for the heart to beat, as you can see from this markedly sluggish zebrafish heart valve.